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2 large, long-term trials (GEM, GuidAge) found no dementia-prevention effect in healthy older adults
Laboratory investigations focus heavily on its ability to stimulate dendritic spine formation, modulate synaptic density, and restore cognitive deficits induced by pharmacological disruptors in preclinical models
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Individuals with sensitive skin may benefit from patch testing before regular use
Therefore, the ratio of GSH and GSSG has been noted as index of oxidative stress
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